Screening of natural products for new leads as inhibitors of beta-amyloid production: Latifolin from Dalbergia sissoo

Authors
Ramakrishna, NVS Kumar, EKSV Kulkarni, AS Jain, AK Bhat, RG Parikh, S Quadros, A Deuskar, N Kalakoti, BS
Citation
Nvs. Ramakrishna et al., Screening of natural products for new leads as inhibitors of beta-amyloid production: Latifolin from Dalbergia sissoo, I J CHEM B, 40(6), 2001, pp. 539-540
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
40
Issue
6
Year of publication
2001
Pages
539 - 540
Database
ISI
SICI code
0376-4699(200106)40:6<539:SONPFN>2.0.ZU;2-1
Abstract
Latifolin 1 isolated from the methylene chloride extract of the heartwood o f Dalbergia sissoo and found to exhibit the inhibition of P-amyloid synthes is with an IC50 of 180 muM.