Brief report: Macrographia in high-functioning adults with autism spectrumdisorder

The initial description of Asperger syndrome commented on the poor handwrit ing and motor coordination difficulties of individuals with this condition. Early descriptions of autism do not remark upon such difficulties. Recent evidence, however, suggests that individuals with both conditions have a si milar motor control impairment. Handwriting has not been formally assessed in this context. Our study compared handwriting size between individuals wi th autism spectrum disorder and age- and IQ-matched control subjects. Macro graphia was observed among subjects with autism spectrum disorder which rem ained statistically significant when covaried with educational level. This finding may correlate with the anatomical abnormalities present in the cere bellum of individuals with autism spectrum disorder.