Synthesis and spectral properties of 2-[(o- and p-substituted)aminophenyl]-3H-5-[(o- and p-substituted)phenyl]-7-chloro-1,4-benzodiazepines

A series of twelve new 2-[(o- and p-substituted)aminophenyl]-3H-5-[(o- and p-substituted)phenyl]-7chloro-1,4-benzodiazepines, which have possible phar macological properties has been obtained. The synthesis was carried out fol lowing six steps. The structure of all products was corroborated by ir, H-1 nmr, C-13 nmr and ms. In addition for the compound 2-(o-chloroaminophenyl) -3H-5-(o-fluorophenyl)-7-chloro-1,4-benzodiazepine 7, its structure was con firmed by X-ray diffraction.