Morphoea in three siblings

Atrophoderma of Pasini and Pierini (APP) is an uncommon form of localized m orphoea that occurs as superficial, hyperpigmented plaques distributed main ly on the trunk and proximal part of the limbs. There is little information about the influence of genetic and environmental factors on disease suscep tibility and expression for localized scleroderma, although APP familial ca ses have been reported.(1) We report three siblings without a family histor y of autoimmune disease presenting cutaneous lesions suggesting morphoea (A PP variant).