PALLADIUM-CATALYZED AMINATION OF 2-CHLORO-1,3-AZOLE DERIVATIVES - MILD ENTRY TO POTENT H-1-ANTIHISTAMINIC NORASTEMIZOLE

Authors
HONG YP TANOURY GJ WILKINSON HS BAKALE RP WALD SA SENANAYAKE CH
Citation
Yp. Hong et al., PALLADIUM-CATALYZED AMINATION OF 2-CHLORO-1,3-AZOLE DERIVATIVES - MILD ENTRY TO POTENT H-1-ANTIHISTAMINIC NORASTEMIZOLE, Tetrahedron letters, 38(32), 1997, pp. 5607-5610
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
32
Year of publication
1997
Pages
5607 - 5610
Database
ISI
SICI code
0040-4039(1997)38:32<5607:PAO2D->2.0.ZU;2-7
Abstract
Palladium-catalyzed selective amination of 4-fluorobenzyl-2-chlorobenz imidazole with 4-aminopiperidine provided a simple solution for the no rastemizole synthesis. Pd-catalyzed amination of other 2-chloro-1,S-Az ole derivatives are exploited. (C) 1997 Elsevier Science Ltd.