DEUTERIUM-LABELED PROCYANIDIN SYNTHESES

Authors
PIERRE MC CHEZE C VERCAUTEREN J
Citation
Mc. Pierre et al., DEUTERIUM-LABELED PROCYANIDIN SYNTHESES, Tetrahedron letters, 38(32), 1997, pp. 5639-5642
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
32
Year of publication
1997
Pages
5639 - 5642
Database
ISI
SICI code
0040-4039(1997)38:32<5639:DPS>2.0.ZU;2-S
Abstract
Deuterium-labeled procyanidins have been prepared by hemisynthesis fro m taxifolin in order to investigate their metabolism in human. The str uctures of the desired deuterated natural compounds B3 10D (R-1=D, R-2 =H) and B4 13D (R-1=D, R-2=H) were proven by spectroscopic and physica l properties means, including H-2 NMR spectrum. By-products with unatu ral absolute configuration at some centers were also formed along the process and were characterised. (C) 1997 Elsevier Science Ltd.