ABSOLUTE-CONFIGURATION OF NORZOANTHAMINE, A PROMISING CANDIDATE FOR AN OSTEOPOROTIC DRUG

Authors
KURAMOTO M HAYASHI K FUJITANI Y YAMAGUCHI K TSUJI T YAMADA K IJUIN Y UEMURA D
Citation
M. Kuramoto et al., ABSOLUTE-CONFIGURATION OF NORZOANTHAMINE, A PROMISING CANDIDATE FOR AN OSTEOPOROTIC DRUG, Tetrahedron letters, 38(32), 1997, pp. 5683-5686
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
32
Year of publication
1997
Pages
5683 - 5686
Database
ISI
SICI code
0040-4039(1997)38:32<5683:AONAPC>2.0.ZU;2-Y
Abstract
The absolute configuration of norzoanthamine (1) was determined to be 2R, 4S, 6S, 9S, 10R, 12R, 13R, 18S, 21S, and 22S based on H-1 NMR spec tral data of the MTPA esters of norzoanthamine derivatives. The possib le biogenesis of zoanthamines is also proposed. (C) 1997 Elsevier Scie nce Ltd.