K. Kaufmann et al., ULTRASOUND DETECTION OF APERT-SYNDROME - A CASE-REPORT AND LITERATURE-REVIEW, American journal of perinatology, 14(7), 1997, pp. 427-430
Apert Syndrome is characterized by craniosynostosis, bilateral syndact
yly, and midfacial hypoplasia. Although it was first described by Whea
ten in 1894, it was first diagnosed prenatally only a decade ago-with
only five cases reported in the literature. A sixth case is reported h
ere. Prenatal diagnosis of Apert syndrome is reviewed.