HERITABILITY OF EPILEPTIC SEIZURES IN THE BELGIAN TERVUEREN

Citation
Tr. Famula et al., HERITABILITY OF EPILEPTIC SEIZURES IN THE BELGIAN TERVUEREN, Journal of Small Animal Practice, 38(8), 1997, pp. 349-352
Citations number
15
Categorie Soggetti
Veterinary Sciences
ISSN journal
00224510
Volume
38
Issue
8
Year of publication
1997
Pages
349 - 352
Database
ISI
SICI code
0022-4510(1997)38:8<349:HOESIT>2.0.ZU;2-8
Abstract
Survey data were collected on the incidence of epileptic seizures in 9 97 Belgian tervuerens. The heritability of this disorder was estimated as 0.77 (with a 95 per cent confidence interval spanning from 0.65 to 0.88) using a Bayesian analysis in an ordered categorical threshold m odel. Single locus models do not appear adequate as an explanation for this inherited seizure disorder. The high heritability estimate sugge sts that breeders can wage a successful battle against this disorder b y breeding unaffected individuals, particularly those from families wi th no history of seizures.