We study the evolution of the flavour non-singlet deep-inelastic structure
functions F-2,F-NS and F-3 at the next-to-next-tu-next-to-leading order ((N
LO)-L-3) of massless perturbative QCD. The present information on the corre
sponding three-loop coefficient functions is used to derive approximate exp
ressions of these quantities which prove completely sufficient for values x
> 10(-2) of the Bjorken variable. The inclusion of the N3LO corrections re
duces the theoretical uncertainty of alpha (s) determinations from non-sing
let scaling violations arising from the truncation of the perturbation seri
es to less than 1%. We also study the predictions of the soft-gluon resumma
tion, of renormalization-scheme optimizations by the principle of minimal s
ensitivity (PMS) and the effective charge (ECH) method, and of the Fade sum
mation for the structure-function evolution kernels. The PMS, ECH and Fade
approaches are found to facilitate a reliable estimate of the corrections b
eyond (NLO)-L-3. (C) 2001 Elsevier Science B.V. All rights reserved.