Patterns of brain metastasis in lung cancer

Brain metastasis as the only site of spread in lung cancer was studied. Nin ety-two (13.1%) of 701 lung cancer patients had blain metastasis at the tim e of diagnosis. Eighteen and 16 patients had small primary Lesion and were N0-1 disease, respectively. Thirty-two patients h:td sole brain metastasis. Patients with sole brain metastasis had more favorable survival than patie nts with other metastatic sites (p=0.0165). Blain metastasis may occur even with small primary lesion and/or without regional lymph node involvement. Well-planned surgery or stereotactic radiosurgery will result in enhanced s urvival.