Purpose: To determine prospectively the accuracy of a predictive risk formu
la for the development of postoperative proliferative vitreoretinopathy (PV
R) when applied in a clinical setting.
Design: Prospective noncomparative interventional case series. Participants
: Two hundred nineteen subjects undergoing primary vitrectomy for rhegmatog
enous retinal detachment were studied.
Method: By use of a formula-based discriminant rule, subjects were classifi
ed as either high or low risk for the development of PVR, All subjects were
followed prospectively.
Outcome Measures: Development of postoperative PVR as defined by the update
d the Retina Society Classification.
Results: Complete data were available on 212 of 219 subjects. There were 13
0 subjects identified as low risk and 82 subjects as high risk; 9.2% of the
low-risk (12 of 130) compared with 28% (23 of 82) of the high-risk subject
s had postoperative PVR develop. This difference was statistically signific
ant (P < 0.001).
Conclusions: Our study has shown that using a clinical model it is possible
to identify subjects at greater risk of PVR developing after primary vitre
ctomy, Ophthalmology 2001;108:1184-1186 (C) 2001 by the American Academy of
Ophthalmology.