Am. Hafez et al., Reactive ketenes through a carbonate/amine shuttle deprotonation strategy:Catalytic, enantioselective alpha-bromination of acid chlorides, ORG LETT, 3(13), 2001, pp. 2049-2051
[GRAPHICS]
We have developed an efficient methodology for the generation of ketenes by
employing a catalytic shuttle base and potassium carbonate as a stoichiome
tric base, We have applied this technology to the catalytic, asymmetric a b
romination of acid chlorides.