Construction of azaspirocyclic ketones through alpha-hydroxyiminium ion oralpha-siloxy epoxide semipinacol rearrangements

Authors
Fenster, MDB Patrick, BO Dake, GR
Citation
Mdb. Fenster et al., Construction of azaspirocyclic ketones through alpha-hydroxyiminium ion oralpha-siloxy epoxide semipinacol rearrangements, ORG LETT, 3(13), 2001, pp. 2109-2112
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
13
Year of publication
2001
Pages
2109 - 2112
Database
ISI
SICI code
1523-7060(20010628)3:13<2109:COAKTA>2.0.ZU;2-P
Abstract
[GRAPHICS] Semipinacol-type rearrangements to produce azaspirocyclic ketones are prese nted. The yields and stereoselectivities of these reactions range from 67-9 4% yield and 2.8:1 to 1:0 diastereoselectivity, respectively.