Raynaud phenomenon after treatment of verruca vulgaris of the sole with intralesional injection of bleomycin

Intralesional injection of bleomycin (BLM) for the treatment of warts resis tant to all conventional therapies is of certain interest because of the dr ug's row toxicity and its efficacy. However, delayed side effects may appea r, particularly Raynaud phenomenon. Accordingly, some precautions must be t aken in patients with vascular or collagen diseases and, as a precaution, p regnant or lactating women and infants should not be treated with this drug .