Main glucosidase conversion products of the gluco-alkaloids dolichantosideand palicoside

Authors
Brandt, V Tits, M Penelle, J Frederich, M Angenot, L
Citation
V. Brandt et al., Main glucosidase conversion products of the gluco-alkaloids dolichantosideand palicoside, PHYTOCHEM, 57(5), 2001, pp. 653-659
Citations number
31
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
57
Issue
5
Year of publication
2001
Pages
653 - 659
Database
ISI
SICI code
0031-9422(200107)57:5<653:MGCPOT>2.0.ZU;2-8
Abstract
The enzymatic glucose cleavage of palicoside revealed the biosynthetic path way to akagerine, whereas the conversion of dolichantoside led to a new qua ternary heteroyohimbine alkaloid named N-b-methyl-21-beta -hydroxy-mayumbin e. The hypothetical models of reactions occurring after the conversion of b oth substrates are proposed. Dolichantoside and palicoside, as well as Stry chnos mellodora a stem bark crude ethanol extract, exhibit significant anti mycotic activity against human pathogens in presence of specific glucosidas e. (C) 2001 Elsevier Science Ltd. All rights reserved.