Pure, homo-bifunctional poly(ethylene glycol) orthogonally protected: synthesis and characterisation

Authors
Drioli, S Benedetti, F Bonora, GM
Citation
S. Drioli et al., Pure, homo-bifunctional poly(ethylene glycol) orthogonally protected: synthesis and characterisation, REACT FUNCT, 48(1-3), 2001, pp. 119-128
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
REACTIVE & FUNCTIONAL POLYMERS
ISSN journal
13815148 → ACNP
Volume
48
Issue
1-3
Year of publication
2001
Pages
119 - 128
Database
ISI
SICI code
1381-5148(20010502)48:1-3<119:PHPGOP>2.0.ZU;2-X
Abstract
New orthogonal reversible protections have been introduced on high-molecula r weight, di-hydroxy PEGs. The introduction on the reaction intermediates o f a removable carboxy group allows an efficient purification from all the u ndesired polymeric derivatives. A final, pure high-molecular weight DMT-PEG -Fmoc has been obtained. (C) 2001 Elsevier Science B.V; All rights reserved .