CORONARY-ARTERY SPASM - A HYPOTHESIS ON PREVENTION BY PROGESTERONE

Authors
KANDA I ENDO M
Citation
I. Kanda et M. Endo, CORONARY-ARTERY SPASM - A HYPOTHESIS ON PREVENTION BY PROGESTERONE, Medical hypotheses, 49(2), 1997, pp. 183-185
Citations number
9
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Medical hypotheses → ACNP
ISSN journal
03069877
Volume
49
Issue
2
Year of publication
1997
Pages
183 - 185
Database
ISI
SICI code
0306-9877(1997)49:2<183:CS-AHO>2.0.ZU;2-M
Abstract
The mechanism of coronary artery spasm has been hypothesized as follow s: the dormant gene of the smooth muscle of the human coronary artery is identical or similar to the active gene of the smooth muscle of duc tus arteriosus, but can be activated by estrogen. The activation could be preventable by progesterone. The prevention is due to the reductio n of the number of estrogen receptors of the smooth muscle of the coro nary artery.