Electronic noses consist of an array of non-selective gas sensors with a pa
ttern recognition engine. The sensors and pattern recognition methods depen
d on the specific application. The design process of electronic noses usual
ly involves time-consuming measurements in a non-standard trial and error p
rocess. This paper addresses the problem by using an electronic nose simula
tion tool centred on PSpice. Using previously developed generic PSpice mode
ls for the response of gas sensors, a four-element tin oxide sensor array w
as simulated. The sensor model parameters were adjusted using calibrated re
sponse data from ethanol, methane and their mixtures, detected with real ti
n oxide sensors. To study the performance of the array, statistical error m
odelling and PSpice simulations were used in a Monte Carlo analysis coupled
with principal component analysis. The results show that this simulation s
trategy is useful for analysing the effects of sampling errors, the changes
in operation temperature, random errors and sensor drift. The importance o
f these errors is discussed in terms of the array discrimination ability. W
e conclude that this simulation strategy can help to systematise the design
of electronic noses. (C) 2001 Elsevier Science B.V. All rights reserved.