Laparoscopic transcystic Sphincter of Oddi manometry is not affected by carbon dioxide pneumoperitoneum

Sphincter of Oddi (SO) dysfunction as a potential cause of chronic acalculo us cholecystitis (CAC) has not been studied in cases for which intraoperati ve SO manometry was used during laparoscopic cholecystectomy. In this study , we evaluated the effects of carbon dioxide pneumoperitoneum on laparoscop ic transcystic SO manometry. In 27 patients with CAC, transcystic SO manome try had been attempted during laparoscopic cholecystectomy. The mean age of the patients was 46 years (range, 22-71). Complete manometric data sets we re obtained in 18 patients. The mean SO pressure, phasic SO pressure, and p hasic frequency were 35.4 +/- 29.1 mm/Hg versus 30.8 +/- 23.8mm/Hg, 104.8 /- 63.0 mm/Hg versus 73.6 +/- 34.6 mm/Hg, and 2.1 +/- 1.8 contractions/min versus 2.8 +/- 3.4 contractions/min with and without pneumoperitoneum, resp ectively. All differences were nonsignificant (P > 0.05). Two complications (7.4%) were observed: pancreatitis and jaundice. SO manometry is not affec ted by CO2 pneumoperitoneum. It may be used to study SO motility in patient s with CAC.