Y. Nakamura et al., Enantioselective addition of diethylzinc to aldehydes catalyzed by fluorous beta-aminoalcohols, TETRAHEDRON, 57(26), 2001, pp. 5565-5571
A fluorous aminoalcohol prepared from ephedrine has been used as a catalyst
for the enantioselective addition of diethylzinc to aldehydes to afford th
e corresponding alcohols in up to 84% ee. The fluorous amino alcohol was ea
sily recovered by a simple filtration through a fluorous reverse phase sili
ca gel and was reusable without purification. (C) 2001 Elsevier Science Ltd
. AU rights reserved.