A convenient allylsilane-N-acyliminium route toward 5-alkylindolizidines. Diastereoselective synthesis of (+/-)-indolizidine 167B

Authors
Peroche, S Remuson, R Gelas-Mialhe, Y Gramain, JC
Citation
S. Peroche et al., A convenient allylsilane-N-acyliminium route toward 5-alkylindolizidines. Diastereoselective synthesis of (+/-)-indolizidine 167B, TETRAHEDR L, 42(28), 2001, pp. 4617-4619
Citations number
35
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
28
Year of publication
2001
Pages
4617 - 4619
Database
ISI
SICI code
0040-4039(20010709)42:28<4617:ACART5>2.0.ZU;2-N
Abstract
A highly diastereostelective synthesis of 5-alkylindolizidines is described via an intermolecular addition of the allylsilyl functional group of homoa llylic alcohols with an N-acyliminium ion derived from pyrrolidin-2-one. (C ) 2001 Elsevier Science Ltd. All rights reserved.