A novel optically based chemosensor for the detection of blood Na+

Authors
Gunnlaugsson, T Nieuwenhuyzen, M Richard, L Thoss, V
Citation
T. Gunnlaugsson et al., A novel optically based chemosensor for the detection of blood Na+, TETRAHEDR L, 42(28), 2001, pp. 4725-4728
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
28
Year of publication
2001
Pages
4725 - 4728
Database
ISI
SICI code
0040-4039(20010709)42:28<4725:ANOBCF>2.0.ZU;2-9
Abstract
The azo dye based chemosensor 2 displays extremely good sensitivity acid se lectivity for Na+ over other physiologically important alkali and alkali ea rth metal ions in the 0.3 1.0 x 10(-4) M concentration range as well as bei ng pH independent above pH 3.9. This sensitivity coincides with the Na+ con centration range found in blood. Thr sensor exhibits almost 110 nm hypsochr omic shift in the absorption spectrum upon Na+ detection, with a strong col our change from red to yellow in aqueous solution which is clearly visible to the naked eye even at low concentrations. (C) 2001 Elsevier Science Ltd. All rights reserved.