Polymer-bound N-hydroxysuccinimide as a solid-supported additive for DCC-mediated peptide synthesis

Authors
Chinchilla, R Dodsworth, DJ Najera, C Soriano, JM
Citation
R. Chinchilla et al., Polymer-bound N-hydroxysuccinimide as a solid-supported additive for DCC-mediated peptide synthesis, TETRAHEDR L, 42(27), 2001, pp. 4487-4489
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
27
Year of publication
2001
Pages
4487 - 4489
Database
ISI
SICI code
0040-4039(20010702)42:27<4487:PNAASA>2.0.ZU;2-H
Abstract
Polymer-supported N-hydroxysuccinimide (P-HOSu) has been prepared from a st yrene/maleic anhydride co-polymer and used as an easily removable activatin g and racemization-reducing additive for the peptide coupling of amino acid derivatives using DCC. (C) 2001 Elsevier Science Ltd. All rights reserved.