The efficiency of extraction of rutin from Sophora japonica is improved by
ultrasound but is dependent on the solvent employed. Rutin is a compound wi
th antioxidant activity and aqueous solvents appear to be unsuitable for ul
trasonic extractions due to the formation of free radicals from the insonat
ion of the solvent. The application of ultrasound to methanolic extraction
gave a significant reduction in extraction time and an increase in maximum
yield. (C) 2001 Elsevier Science B.V. All rights reserved.