Gregg phenomenon and gardenhose effect

Citation
Jd. Schipke et D. Frehen, Gregg phenomenon and gardenhose effect, Z KARDIOL, 90(5), 2001, pp. 319
Citations number
89
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
ZEITSCHRIFT FUR KARDIOLOGIE
ISSN journal
03005860 → ACNP
Volume
90
Issue
5
Year of publication
2001
Database
ISI
SICI code
0300-5860(200105)90:5<319:GPAGE>2.0.ZU;2-B
Abstract
Under physiologic circumstances, cardiac function determines myocardial oxy gen consumption and consequently coronary perfusion. Surprisingly, in a rev erse direction, improved coronary perfusion also increased myocardial oxyge n consumption and contractile function. This experimental finding, now 40 y ears old, is termed the Gregg phenomenon. Some 10 years later, in experimen ts by Arnold and coworkers, an isolated increase in perfusion pressure impr oved ventricular function. In this context, the term 'gardenhose effect' wa s coined, implying a hydraulic explanation of the Gregg phenomenon. In the following, we attempt to distinguish the Gregg phenomenon from the g ardenhose effect and to critically evaluate them.