Metal complexes of biologically important ligands, CXXXVII [1]. Halfsandwich complexes with N,O-chelates and Schiff bases of beta-amino acids

beta -Phenylalanine forms with chloro bridged complexes the chiral N,O-chel ates Cp*Ir(Cl)(NH2CH(Ph)CH2CO2) and (p-cymene)Ru(Cl)(NH2CHPhCH2CO2) as mixt ure of two diastereoisomers. Similarly the palladium(III) and platinum(II) complexes (Et3P)(Cl)M(NH2CH(Ph)CH2CO2) (M = Pd, Pt) were obtained. Schiff b ase complexes (arene)(Cl)M(O2CC(R)=N-CH(R)CH(R)CH2CO2CH3) (arene = Cp*, p-c ymene; M = Ir, Ru) were synthesized from the chloro-bridged compounds, 2-ox ocarboxylates and beta -alanine or beta -phenylalanine methylester. The Cp* Ir complex with a tridendate dianionic Schiff base generated from pyruvate and beta -phenylalaninate is obtained as a single isomer. Cp*Ir(Cl) forms a complex with an N,O-bidentate Schiff base ligand from glycinate and acetyl acetic ethyl ester.