Cell density-correlated induction of pyruvate decarboxylase under aerobic conditions in the yeast Pichia stipitis

Citation
M. Mergler et U. Klinner, Cell density-correlated induction of pyruvate decarboxylase under aerobic conditions in the yeast Pichia stipitis, ACT BIOL HU, 52(2-3), 2001, pp. 265-269
Citations number
13
Categorie Soggetti
Biology
Journal title
ACTA BIOLOGICA HUNGARICA
ISSN journal
02365383 → ACNP
Volume
52
Issue
2-3
Year of publication
2001
Pages
265 - 269
Database
ISI
SICI code
0236-5383(2001)52:2-3<265:CDIOPD>2.0.ZU;2-Z
Abstract
During the aerobic batch cultivation of P. stipitis CBS 5776 with glucose, pyruvate decarboxylase was activated in a cell number-correlated manner. Ac tivation started when a cell number between 7x10(7) and 1x10(8) cells ml(-1 ) was reached and the enzyme activity increased during further cultivation. This induction might have been triggered either by an unknown quorum sensi ng system or by a shortage of cytoplasmic acetyl-CoA.