E. Vainio et al., Endovascular surgery for chronic limb ischaemia. Factors predicting immediate outcome on the basis of a nationwide vascular registry., ANN CHIR GY, 90(2), 2001, pp. 86-91
Purpose: To evaluate the early results of endovascular treatment of chronic
limb ischemia and the factors influencing outcome.
Methods: The 5,575 endovascular procedures entered into the national vascul
ar registry in 1991-1994 were reviewed retrospectively. Indication was clau
dication in 3,873 and chronic critical ischemia (CLI) in 1,702 procedures.
In CLI most patients were women and older, with a higher proportion of diab
etes mellitus, renal insufficiency and coronary heart disease than in claud
ication group although the incidence of smoking and hyperlipidaemia was low
er. 60.2% of the procedures were performed in femoropopliteal arteries, 24.
9% in iliac arteries and 14.9% in infrapopliteal arteries. The followup was
30 days.
Results: In the claudication group there was clinical improvement in 2,719
(82.8%) and in the CLI group in 851 (70.9%) of patients. Patency was better
in the claudication than in CLI group, 94.6% vs. 89.0% respectively. There
was hemodynamic improvement, i.e. improvement of the ankle-brachial index
of more than 0.15 in 1,680 (58.2%) patients with claudication and in 437 (5
9.7%) with CLI. In a logistic regression model diabetes mellitus and renal
insufficiency increased the relative risk of amputations and mortality in C
LI group, whereas, incidence of amputations was lower in patients with hype
rlipidaemia. In claudication group femoropopliteal arteries had an adverse
effect on patency.
Conclusion: The clinical characteristics of the groups may explain some of
the outcome differences. Angioplasty is recommended to be used in the femor
opopliteal arteries if the symptoms are severe and in CLI group with diabet
es and renal failure only in selected cases.