Magnetocardiographic and electrocardiographic exercise mapping in healthy subjects

In 12-lead electrocardiography (ECG), detection of myocardial ischemia is b ased on ST-segment changes in exercise testing. Magnetocardiography (MCG) i s a complementary method to the ECG for a noninvasive study of the electric activity of the heart. In the MCG, ST-segment changes due to stress have a lso been found in healthy subjects. To further study the normal response to exercise, we performed MCG mappings in 12 healthy volunteers during supine bicycle ergometry. We also recorded body surface potential mappings (BSPM) with 123 channels using the same protocol. In this paper we compare, for t he first time, multichannel MCG recorded in bicycle exercise testing with B SPM over the whole thorax in middle-aged healthy subjects. We quantified ch anges induced by the exercise in the MCG and BSPM with parameters based on signal amplitude, and correlation between signal distributions at rest and after exercise. At the ST-segment and T-wave apex, the exercise induced a m agnetic field component outward the precordium and the minimum value of the MCG signal over the mapped area was found to be amplified. The response to exercise was smaller in the BSPM than in the MCG. A negative component in the MCG signal at the repolarization period of the cardiac cycle should be considered as a normal response to exercise. Therefore, maximum ST-segment depression over the mapped area in the MCG may not be an eligible parameter when evaluating the presence of ischemia.