DIAGNOSIS OF CEREBRAL VENTRICULOMEGALY IN NORMAL ADULT BEAGLES USING QUANTITATIVE MRI

The brain of 17 asymptomatic normal adult beagles was evaluated with m agnetic resonance imaging, Lateral ventricular size was quantified usi ng computer algorithms, In beagles,vith large ventricles, contrast med ium was introduced into the cerebellomedullary cistern to determine wh ether obstructive hydrocephalus was present, Total lateral ventricular volume ranged from 77 mm(3) to 11,726 mm(3), Based on Gd-DTPA diffusi on, the CSF flow pattern was considered normal and normal neural morph ology was seen using electron microscopy, Results suggest a high incid ence of clinically asymptomatic ventriculomegaly in normal adult beagl es.