In naturally gastrointestinal nematodes infected horses the anthelmintic ef
ficacy of the endectocides invermectin (IVM). doramectin (DRM) and moxidect
in (MXD) was evaluated. Animals were evenly distributed to 4 experimental g
roups: Group 1. non treated horses. control: Group II treated with an oral
dose of 0.2 mg/kg of IVM by oral route: Group III treated with a reformulat
ed oral dose of 0.2 mg/kg of DRM: Group IV treated with on oral dose of 0.4
mg/kg of MSD. Faecal samples for parasites eggs count and larval cultures
were collected before treatment at 3,6,10,20,40,60,90,105,125,145 and 175 d
ays postreatment. Results obtained showed a significant reduction (p <0.05)
in the faecal eggs count in treated group. from day 3 to day 145 post trea
tment. This level of significant remained until day 175 post treatment only
in the group treated with moxidectin.