Transcatheter closure of atrial septal defect using amplatzer septal occluder in Chinese adults

Amplatzer septal occluder (AGA Med. Co., USA) is a novel device for occlusi on of atrial septal defect. We present our experience of transcatheter clos ure of atrial septal defects using Amplatzer septal occluder in 45 adult Ch inese patients (age range 18-69 years). The sire of atrial septal defect va ried from 14-28 (23 +/- 4) mm, Cardiac catheterization revealed a pulmonary -to-systemic shunt ratio ranging from 1.4-2.8 (mean 2.0 +/- 0,4). The proce dure was successful in 44 (98%) patients. Displacement of the device requir ing surgical removal occurred in one (2%) patient and minor wound complicat ion occurred in two (4%) patients. Total procedure time was 67 +/- 16 minut es and the fluoroscopy time was 25 +/- 8 min. Immediate post-procedure and pre-discharge echocardiography revealed complete abolition of shunt in 42 ( 93%) and trivial residual shunt in 3 (7%) patients. The average follow-up p eriod was 16 +/- 6 months (range 2 months to 3 years) months. None of the p atients had developed other major complication at follow-up. (C) 2001 Wiley -Liss, Inc.