Catalytic enantioselective addition of aromatic amines to enones: synthesis of optically active beta-amino acid derivatives

Authors
Zhuang, W Hazell, RG Jorgensen, KA
Citation
W. Zhuang et al., Catalytic enantioselective addition of aromatic amines to enones: synthesis of optically active beta-amino acid derivatives, CHEM COMMUN, (14), 2001, pp. 1240-1241
Citations number
21
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
14
Year of publication
2001
Pages
1240 - 1241
Database
ISI
SICI code
1359-7345(2001):14<1240:CEAOAA>2.0.ZU;2-S
Abstract
A catalytic enantioselective addition of aromatic amines to enones has been developed; the potential of the reaction is shown for aromatic amines reac ting with alkyl oxazolidinones in good yield and with moderate to excellent enantiomeric excess, and the transformation of the products to beta -amino acid amides.