Synthesis and application of dimeric Cinchona alkaloid phase-transfer catalysts: alpha,alpha '-bis[O(9)-allylcinchonidinium]-o, m, or p-xylene dibromide

Authors
Jew, SS Jeong, BS Yoo, MS Huh, H Park, HG
Citation
Ss. Jew et al., Synthesis and application of dimeric Cinchona alkaloid phase-transfer catalysts: alpha,alpha '-bis[O(9)-allylcinchonidinium]-o, m, or p-xylene dibromide, CHEM COMMUN, (14), 2001, pp. 1244-1245
Citations number
23
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
14
Year of publication
2001
Pages
1244 - 1245
Database
ISI
SICI code
1359-7345(2001):14<1244:SAAODC>2.0.ZU;2-B
Abstract
A dimeric Cinchona alkaloid ammonium salt, alpha,alpha'-bis[ O( 9) allylcin chonidinium]- m-xylene dibromide 4, has been developed as a new efficient p hase-transfer catalyst; the catalytic enantioselective alkylation of N-(dip henylmethylene)glycine tert-butyl ester using 4 provided 7 in a high enanti omeric excess (90-99% ee).