Despite a totality of evidence indicating clear benefits of statin therapy
in secondary and primary prevention of cardiovascular disease (CVD), a larg
e number of additional trials are currently planned or in progress to help
us better understand, treat, and prevent CVD. Both monotherapy and combinat
ion statin regimens are being studied to optimize treatment of the total pa
tient and to assess mechanisms and benefits of various components of the to
tal lipid profile.