Visceral involvement in eosinophilic fasciitis (EF) is a well known but rar
e event. With regard to neurological manifestations, both carpal tunnel syn
drome and peripheral neuropathy have been described. We report the case of
a 40-year-old woman with EF who had a major motor seizure. This association
might not be fortuitous and be related to the known neurotoxin of eosiaoph
ils.