We analyzed the data from 1821 patients (2920 eyes) who received photo
refractive keratectomy (PRK) to investigate the postoperative complica
tions which cause a significant decrease in visual acuity. A corneal h
aze of grade 2 or more developed in 9 patients (11 eyes, 0.38%) and co
rticosteroid-induced ocular hypertension occurred in 3 patients (4 eye
s, 0.14%). Three patients (4 eyes) who had corneal haze of grade 2 or
more underwent repeated photorefractive keratectomy and one patient (2
eyes) with steroid-induced ocular hypertension underwent trabeculecto
mies. A decrease of best spectacle corrected visual acuity of two line
s or more was detected in 7 patients (8 eyes, 0.27%), caused by irregu
lar astigmatism, steroid-induced cataract, incidental choroidal neovas
cular membrane, and an unknown origin. Good predictability and stabili
zation after photorefractive keratectomy was maintained at the 2 year
follow-up. However, some subjective symptoms were reported by many pat
ients and some complications occurred in a minority of eyes despite th
e excellent visual outcome in a large majority.