Membrane traffic: How do GGAs fit in with the adaptors?

Authors
Black, MW Pelham, HRB
Citation
Mw. Black et Hrb. Pelham, Membrane traffic: How do GGAs fit in with the adaptors?, CURR BIOL, 11(12), 2001, pp. R460-R462
Citations number
22
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
12
Year of publication
2001
Pages
R460 - R462
Database
ISI
SICI code
0960-9822(20010626)11:12<R460:MTHDGF>2.0.ZU;2-B
Abstract
The AP-1 adaptor complex has been cast as the major player in clathrin coat formation for vesicular transpirt from the trans-Golgi to the endocytic pa thway. But new results on 'GGA' proteins have raised doubts about this para digm and suggest both a new sorting mechanism and an unexpected complexity in the roles of clathrin. (C) 2001 Elsevier Science Ltd. All rights reserve d.