In the past two years, the focus of studies of the genes controlling expres
sion of defense responses in Arabidopsis has shifted from the identificatio
n of mutants to gene isolation and the ordering of genes within branches of
the signal transduction networks. It is now clear that gene-for-gene resis
tance can be mediated through at least three genetically distinguishable pa
thways, Additional genes affecting salicylic-acid-dependent signaling have
been identified, and double-mutant analyses have begun to reveal the order
in which they act. Genes required for jasmonic-acid-dependent signaling and
for induced systemic resistance have also been identified.