Objective: The intraoperative measurement of the coronary bypass flow enabl
es the identification of technical errors while the sternum is still open.
The transit-time flow method is able to effectively measure the internal th
oracic artery graft flow. The aim of the present study was to analyze the f
actors which affected the bypass flow rate. Methods: We measured the blood
flow of 291 in situ internal thoracic artery (ITA) and 190 saphenous vein (
SV) grafts constructed in 171 patients undergoing coronary artery bypass gr
afting from December 1996 to March 2000 using this method during the surger
y. All patients underwent postoperative coronary angiography before the pat
ients were discharged. The blood Row rate of all bypass grafts constructed
was assessed after the patients were weaned from cardiopulmonary bypass. Re
sults: The mean flow rate of all ITA grafts was 65.1 +/- 36.7 ml/min and th
at of all SV grafts was 56.4 +/- 29.9 ml/min. According to analyses using c
orrelation tests, the graft flow was found to significantly correlate with
the grafted perfusion areas and the diameter of the bypassed coronary arter
ies. However, no significant difference was observed between the flow rates
of the ITA grafts with and without stenosis or string phenomenon, but sign
ificant (P < 0.0001) correlation was observed between the occurrence of a s
tring sign and the degree of proximal stenosis of the recipient coronary ar
tery. Regarding SV grafts, the mean flow rate of occluded grafts (29.2 <plu
s/minus> 20.5 ml/min) was significantly (P < 0.0001) less than non-occluded
grafts (56.4 <plus/minus> 29.9 ml/min). Conclusions: The bypass flow was a
ffected by such a large number of factors that only measuring the bypass fl
ow rate could not sufficiently predict either stenosed or narrowed grafts.
However, ITA grafts bypassed to the coronary arteries with less stenosis we
re shown to more easily become narrowed. (C) 2001 Elsevier Science B.V. All
rights reserved.