Pathological documentation of complete elimination of Barrett's metaplasiafollowing endoscopic multipolar electrocoagulation therapy

The previous paradigm that Barrett's is an irreversible premalignant lesion has recently been challenged by a proliferation of reports documenting eli mination of Barrett's by a variety of endoscopic techniques. Whether Barret t's is entirely eliminated is unknown as endoscopic biopsy samples the surf ace of the epithelium only. Numerous reports document underlying specialise d columnar epithelium in many of these trials. Until now there have been no reports of pathological examination of the entire oesophagus as a specimen . This case documents complete elimination of intestinal metaplasia from th e oesophagus and supports the biological plausibility of these research tec hniques.