Biology-based combined-modality radiotherapy: Workshop report

Purpose: The purpose of this workshop summary is to provide an overview of preclinical and clinical data on combined-modality radiotherapy. Methods and Materials: The 8th Annual Radiation Workshop at Round Top was h eld April 13-16, 2000 at the International-Festival Institute (Round Top, T X). Results: Presentations by 30 speakers (from Germany, Netherlands, Australia , England, and France along with U.S. participants and M.D. Anderson Cancer Center faculty) formed the framework for discussions on the current status and future perspectives of biology-based combined-modality radiotherapy. Conclusion: Cellular and molecular pathways available for radiation modific ation by chemical and biologic agents are numerous, providing new opportuni ties for translational research in radiation oncology and for more effectiv e combined-modality treatment of cancer. (C) 2001 Elsevier Science Inc.