H. Wertheim et al., Improved detection of methicillin-resistant Staphylococcus aureus using phenyl mannitol broth containing aztreonam and ceftizoxime, J CLIN MICR, 39(7), 2001, pp. 2660-2662
We tested a phenyl mannitol broth containing ceftizoxime and aztreonam (PHM
B+) for detection of methicillin-resistant Staphylococcus aureus (MRSA) wit
h reference MRSA strains and, subsequently,with clinical samples (n = 1,098
). All reference MRSA strains induced color change in PHMB+ after 24 to 72
h of incubation. In a clinical setting, 40 MRSA strains were detected with
PHMB+, compared with only 23 detected with a routine method. Thus, this sel
ective broth significantly (P < 0.001) improved the rate of MRSA detection.