Pancreatic tuberculosis is a rare condition which should be considered in p
atients with a pancreatic mass, particularly if the patient is young, not j
aundiced, from an area of high TB prevalence with a normal ERCP. We report
a case of pancreatic tuberculosis due to Mycobacterium tuberculosis with re
duced sensitivity to rifampicin and isoniazid, that was treated with rifabu
tin, ciprofloxacin, ethambutol and pyrazinamide following clinical failure
of first-line therapy. The case presented illustrates the importance of obt
aining material for culture and sensitivity testing in cases of suspected T
B, (C) 2001 The British Infection Society.