A 2-year-old boy had been operated on for a giant renal cell carcinoma incl
uding splenectomy because of disrupture of the splenic capsule. During a fo
llow-up examination, 3 nodules were detected by ultrasound in the splenoren
al area. This gave reason to suspect tumor recurrence. Considering the poss
ibility of splenosis, a selective spleen scan using denatured red blood cel
ls was performed as a final diagnostic step. This method confirmed the nodu
les as representing splenic tissue. Splenosis should be included in the dif
ferential diagnosis of solid masses in the postsplenectomy patient. Copyrig
ht (C) 2001 by W.B. Saunders Company.