Oedematous skin disease of buffalo in Egypt

This review covers a historical view and etiology of oedematous skin diseas e which affects buffalo in Egypt, the microbiology of Corynebacterium,pseud otuberculosis causing the disease: its virulence; clinical signs; mechanism of pathogenesis; histopathology; mode of transmission; immunological aspec ts; treatment and control. It is concluded that C. pseudotuberculosis serot ype II is the main cause of OSD and exotoxin phospholipase D and its lipid contents of the cell wall are the major causes of pathogenesis. After decla ring the role of Hippobosca equina in transmission of the causative agent a mong buffaloes, control of OSD is now available.