Effect of herb supplement on hepatic enzyme activities in ddY mice

Plasma glucose and lipid concentrations and hepatic enzyme activities were measured in male ddY mice supplemented with the herb, Echevaria glauca, to examine the effect of herbal treatment. In mice supplemented with the herb, plasma triglyceride (TG) and free fatty acid (FFA) concentrations decrease d and hepatic glycolytic enzyme and glutathione peroxidase (GSHpx) activiti es increased significantly compared with those in the nontreated control mi ce. These increases in hepatic enzyme activities were not fully dose-depend ent, however the higher dose and longer duration with herb supplement induc ed increases in the enzyme activities. It was found that dietary herb suppl ement caused an acceleration of hepatic function, judged by increased activ ities of glycolytic enzyme and GSHpx in ddY mice.