Science is an intensely social activity. Professional relationships are ess
ential for scientific success and mentors are indispensable for professiona
l growth. Despite the scientific ethos of universalism and inclusion, Ameri
can women scientists frequently experience isolation and exclusion at some
time during their academic career. By contrast, male scientists enjoy infor
mal but crucial social networks. Female scientists develop necessary strate
gies and defences, but many leave or achieve less success in science when d
eprived of necessary interpersonal connections. There is indication that ch
ange within departments is occurring, but this is dependent upon institutio
nal leadership.