Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency

Authors
Nathanson, S Fremeaux-Bacchi, V Deschenes, G
Citation
S. Nathanson et al., Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency, PED NEPHROL, 16(7), 2001, pp. 554-556
Citations number
16
Categorie Soggetti
Pediatrics
Journal title
PEDIATRIC NEPHROLOGY
ISSN journal
0931041X → ACNP
Volume
16
Issue
7
Year of publication
2001
Pages
554 - 556
Database
ISI
SICI code
0931-041X(200107)16:7<554:SPTIHU>2.0.ZU;2-3
Abstract
A patient with homozygous factor H deficiency presented with hemolytic urem ic syndrome (HUS) at the age of 7 months. After a 2-year period of stabilit y, renal failure and erythrocyte fragmentation recurred between the age of 3 and 4 years. Fresh frozen plasma infusions allowed renal function to be i mproved and erythrocyte fragmentation to be stopped. Withdrawal of plasma t herapy led to a relapse of the biological signs of HUS.